Green synthesis and characterization of silver nanoparticles using belladonna mother tincture and its efficacy as a potential antibacterial and anti-inflammatory agent

Abstract

Abstract Biosynthesized silver nanoparticles is a promising area of interest for researchers of nano biosciences due to its wide range of applications and possibilities in biomedical sciences. Despite, the use of various biological compounds in green synthesis of silver nanoparticles, still there is a huge scope of further improvement for synthesizing stable and broadly applicable silver nanoparticles. Majorly biosynthesized silver nanoparticles have assessed as an antibacterial agent ignoring their other biological applications. So this present study aims to point the application of biosynthesized silver nanoparticles as an anti-inflammatory agent and probably is the first report where capability of Belladonna mother tincture to reduce AgNO3 to Ag-Nanoparticles has been evaluated. The nanoparticles were characterized by UV–Vis spectroscopy, DLS, XRD and zeta potential measurements, and morphology was analysed by SEM and TEM. Anti-bacterial, anti-inflammatory and cytotoxicity effect of the synthesized nanoparticles was also evaluated. Thus, this possibly will be a novel environment-friendly technique to biosynthesize silver nanoparticles by a cost-effective and non-toxic manner.