Abstract

Organoselenium chemistry involves unique methods for the preparation of reaction intermediates and biologically relevant compounds. However, common methods frequently have drawbacks such as the use of halogenated volatile solvents, expensive catalysts systems and sophisticated experimental fittings. Therefore, sustainable organoselenium chemistry is developing. Here, we review green solvent alternatives in organoselenium chemistry. We present the application of the ionic liquids and deep eutectic solvents in the synthesis of seleno-functionalized molecules under mild reaction conditions; the application of polyethylene glycol, glycerol and ethanol as solvents; and the use of organoselenium compounds as starting materials for the preparation of ionic liquids.

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