Abstract

The present study successfully investigated the green synthesis of silver nanoparticles (Ag NPs) using the methanolic extract of the aerial parts of Lavandula coronopifolia. The formation of Ag NPs was confirmed through color change as well as the UV/visible spectra. Further, characterizations were achieved using Fourier Transforms infrared spectroscopy (FT-IR), transmission electron microscope (TEM), thermal gravimetric analysis (TGA), and dynamic light scatting measurements (DLS). The collected isolates (twelve isolates) were identified microscopically as 8 Candida and 4 Aspergillus isolates. The Ag NPs exhibited excellent antifungal activity results against tested isolates compared with L. coronopifolia extract and the antifungal standard (Ketoconazole) with p < 0.01. Ag NPs showed highly significant results towards C. albicans, C. tropicalis, A. fumigatus, and A. niger with MICs ranges of 1.7–0.7 μg/ml (p < 0.01). Depending on the stability and the effective diameters of the prepared Ag NPs using L. coronopifolia extract, it could be used as a simple, green preparation, eco-friendly, and low costs process that can be applied to the veterinary sector.

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