Green multifunctional palladium nanoparticles from polysaccharide cordia myxa (CMY) gum: Synthesis, characterization, and antibacterial activity

Abstract

BackgroundGreen synthesis has emerged as an environmentally friendly and highly effective method that has gained widespread application across various domains and biomedical research, particularly in healthcare. ObjectivesThe primary aim behind synthesizing CMY-PdNPs was to harness the potential of Cordia myxa gum to create multi-functional palladium nanoparticles, which could effectively prevent antimicrobial activity. MethodsIn this study, CMY-PdNPs were synthesized using Cordia myxa gum, a natural polysaccharide known for its non-toxic and environmentally friendly properties, marking the first reported instance of such green synthesis. Remarkably, this synthesis method demonstrated effectiveness in reaction time and nanoparticle stability, achieved without requiring external stabilizers or reducing agents. Green synthesized CMY-PdNPs characterization by different techniques, UV-Vis, FT-IR, FESEM, XRD, TEM, and XPS. ResultsThe synthesized CMY-PdNPs showed UV–Vis absorption maximum at around 278 nm. The crystalline nature of CMY-PdNPs was suggested by XRD patterns at (111), (200 (220), and (311) lattice planes, with a face-centered cubic structure depicting the formation of PdNPs. The chemical composition and product purity of green-produced CMY-PdNPs were determined by XPS analysis. As indicated by TEM micrographs, the uniform and spherical-shaped NPs with an average mean diameter of 15 nm were observed. The study investigated the antibacterial properties of PdNPs against Gram-positive and Gram-negative bacterial strains using the disc diffusion method to assess the zone of inhibition against various pathogenic microorganisms. ConclusionThis work demonstrates that eco-friendly technology can rival conventional physical/chemical methods for PdNP synthesis. Biogenic CMY-PdNPs show exceptional antimicrobial effectiveness and hold promise for biomedical applications, contributing significantly to medical research potential.