Abstract
The plant based synthesis of nanoparticles are highly recommended because of its low toxicity, low cost and eco-friendly nature. In present work, synthesis of silver nanoparticles (AgNPs) involves a bioreduction technique using the aqueous extract derived from the leaves of Pseuderanthemum reticulatum. The synthesized AgNPs were characterized by UV-visible, FT-IR, EDAX, XRD, SEM, TEM, zeta potential analysis and particle size analyzing techniques. The results showed the characteristic absorbance peak at 404 nm in the UV-visible spectrum, the strong signals observed in the EDAX spectrum and the other characterization confirmed the formation of AgNPs with an average particle size of 17.83 nm. The in vitro antioxidant activity of AgNPs by DPPH method results revealed that they have greater radical scavenging capacity with the IC50 value of 101.5 µg/mL. Additionally, the anti-aging activity was also determined by collagenase inhibition assay. The biogenic AgNPs established its strong anti-aging efficacy as demonstrated by their inhibitory capacity against Actinomyces israelii (collagenase enzyme). Since, the AgNPs synthesized using aqueous extract of P. reticulatum exhibited leaves excellent antioxidant and anti-aging activity, it can be promising choice for various biological applications.
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