Green Bioanalytical Methods Are Now A Reality

Abstract

BioanalysisVol. 4, No. 11 Special Focus: Green bioanalysis - ForewordFree AccessGreen bioanalytical methods are now a realityOlivier HeudiOlivier HeudiDMPK/Bioanalytics & Biotechnology Development, Forum 1 Novartis Campus, Novartis Pharma AG, Basel, Switzerland. Search for more papers by this authorEmail the corresponding author at olivier.heudi@novartis.comPublished Online:21 Jun 2012https://doi.org/10.4155/bio.12.112AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit Keywords: bioanalysisenvironmentgreengreen chemistryThe conclusions of the recent conference on climate held in Durban, South Africa, were not really reassuring with regards to the current state of our planet. In fact several voices have arisen to ask a number of urgent measures in order to preserve our planet by reducing the use of hazardous chemicals and polluting processes in various fields of activity. In this respect, several polluting industries have been designated. Moreover, it has been suggested to claim a financial compensation to the more polluting industries. In the field of chemistry, and particularly the one of bioanalysis, there has been a concern about the use of hazardous chemicals and, thus, new concepts have been developed in order to reduce waste and replace the most polluting solvents. In this respect, the notion of green chemistry has emerged in all steps of bioanalysis, from the sample withdrawal, storage and analysis. Thus, the continuous effort in green bioanalytical methods is reflected by several scientific contributions from a variety of research groups, and it is appropriate that Bioanalysis dedicates a special focus issue to green bioanalytical methods.In the present issue we include a wide selection of research, review and editorial papers focusing on green bioanalytical methods and laboratory practices. The editorial papers discuss new green bioanalytical methods in the drug-discovery and -development field. They put emphasis on sample preparation, with the development of solid-phase microextraction and supercritical fluid chromatography, reduction of sample collection using techniques, such as dried blood spot sampling, and replacement of conventional LC mobile phase, such as acetonitrile by ethanol, which is less polluting. The research papers deal with real examples of green bioanalytical implementation in the field of sample collection, extraction or preparation and analysis (with or without chromatography) as well as reduction of sample size.Overall, it is clear from the articles in this issue that the interest in green bioanalytical methods is growing in the drug-discovery and -development field. Green methods and practices can also lead to more efficient, cost-effective bioanalytical laboratories. In the near future, we will certainly see developments and new methods in this arena. I would like to thank all the authors for their contributions to this issue, and hope that it contributes, in some small way, to improving our environment.Financial & competing interests disclosureThe author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.FiguresReferencesRelatedDetailsCited ByUHPLC-MS/MS assay using environment friendly organic solvents: A green approach for fast determination of quetiapine in rat plasmaArabian Journal of Chemistry, Vol. 12, No. 7 Vol. 4, No. 11 Follow us on social media for the latest updates Metrics History Published online 21 June 2012 Published in print June 2012 Information© Future Science LtdKeywordsbioanalysisenvironmentgreengreen chemistryFinancial & competing interests disclosureThe author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download