Greater obesity among breast cancer cases compared to controls from the Breast Cancer Risk Model in Pacific Islander Study in Guam and Saipan (628.8)

Abstract

The BRISK study compared BMI and waist circumference measurements of breast cancer cases (n=107) versus controls (n=184). In this case‐control study of women (n=291) living on Guam and Saipan, demographic, medical history and anthropometric measurements, including height, weight, and waist circumference were collected from each participant. BMI was classified as obese (BMI蠅30), overweight (BMI 25‐29.9), or healthy weight (BMI<25). A waist‐for‐height ratio greater than 0.5 was used to classify participants as ‘at risk’. Cases and controls did not differ in body weight (μ=74.3kg) or BMI (μ = 30.4). However, waist circumference was higher (p<0.05) among cases versus controls (100.1 cm versus 95.8 cm). A higher proportion of controls were ‘healthy weight’ (BMI<25) compared to cases (29.2% versus 18.5%); cases were more likely to be either ‘overweight’ and/or ‘obese’ compared to controls. A high proportion of both cases and controls were classified ‘at risk’, as indicated by waist‐for‐height measurements (97.5% and 87.1%), and a higher proportion of cases vs controls were considered ‘at risk’. Anthropometric data suggests that both breast cancer cases and controls are at elevated risk for chronic disease, though cases have higher levels than controls.Grant Funding Source: Supported by a NCI MI/CCP Grant #U54‐CA‐143727