Abstract
The purpose of this review is to examine epigallocatechin-3-gallate (EGCG) regarding its stability in different conditions (pH-value, concentration, temperature), its interactions with common cosmetic ingredients, and its application in the dermatological field. The literature research considered published journal articles (clinical trials and scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) and reference lists of respective articles. Higher concentrations of EGCG were reported to correlate with better stability and the same can be said for low temperatures and pH values. The interaction between EGCG and hyaluronic acid strengthens its antioxidant activities. Titanium dioxide coated with EGCG proved a suitable ingredient in sunscreens. The polyphenol possesses antioxidant properties, which proved effective in the prevention of UV-induced skin damage and to alleviate the symptoms of Imiquimod-induced psoriasis. The three endpoints of this review not only showed interesting results but also highlighted some limitations of EGCG. Studies show that the molecule is unstable, which may hinder its dermatological and cosmetic applications. The reported interactions with cosmetic ingredients were limited. As the health aspects of EGCG are well-reported, ECGC has become a focus of interest for health professionals trying to treat common dermatological diseases.
Highlights
Epigallocatechin-3-gallate (EGCG) is the most abundant catechin in green tea
We examined the literature with the purpose of analyzing the molecule in the context of its stability, its interaction with common cosmetic ingredients, and its health benefits
We focused on studies that examined the EGCG in its unaltered form and not coated with another substance
Summary
Epigallocatechin-3-gallate (EGCG) is the most abundant catechin in green tea. The molecule is known for its many properties, which vary from antiangiogenic and anticarcinogenic to antioxidant, antimicrobial, and anti-inflammatory (Chakrawarti, Agrawal, Dang, Gupta, & Gabrani, 2016). Many common cosmetic ingredients can enhance EGCG stability and its properties. We examined the literature with the purpose of analyzing the molecule in the context of its stability, its interaction with common cosmetic ingredients, and its health benefits.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
