Abstract
肺癌从传统化疗到分子靶向,再到如今免疫治疗的转变,转化性研究发挥着无可替代的作用,其中图表演化更是见证一次次重大变迁,从“森林图”到“生存曲线图”,“瀑布图”,“蜘蛛图”再到最近的“时间线区域面积图”,纵向展示了肺癌治疗从群体逐渐向个体深入细化的理念和演进过程。尽管目前最新的免疫治疗炙手可热,但其研究结果并没有达到预期理想,同时传统的治疗手段仍然存在局限性,需要更深入探索。本文将从图表演化角度论述肺癌转化性研究的发展历程,剖析部分失败的外科临床研究,以期对未来肺癌治疗及图表演化有所启发。
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