Abstract

In recent years, graphene has drawn significant interest in the scientific community and is being investigated for many biomedical applications in the future. Among nanomaterials based on graphene, graphene oxide and reduced graphene oxide are talented applicants for cancer therapy. GO or rGO play either a role of nanocarrier or active agent for advanced chemotherapy delivery in cancer treatment because they have specific physical, chemical and optical properties which include tremendously large surface area, active modifiable groups on their surface, excellent biocompatibility and it does not produce any toxic effect when exposed to body and show good photothermal (PT) effect. In an increasing number of medical submissions, like diagnosis of a disease, chemotherapy, transfection of genetic material or antibodies and even in tissue engineering, graphene/graphene oxide have been explored with ultimate goal of using it as a theranostic material. In the present review article, an overview of the latest studies using graphene-based nanomaterials and their composites in cancer therapy, particularly, in drug delivery system (DDS) and bioimaging are highlighted.

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