Abstract

The paper presents flexible graphene oxide (GO)-Chitosan composite based biosensor for electrochemical detection of dopamine (DA). Electrochemical redox based detection tool for analytes has gained popularity due to their high specificity, sensitivity and label free technique. The GO-Chitosan based electrochemical electrodes presented here for three-electrode voltammetry have Ag/AgCl and Platinum based reference and counter electrode, respectively. The cyclic voltammetry (CV) of DA with as prepared electrode show quasi-reversible behaviour with characteristic cathodic peak (7 pc ) at +200mV and anodic peak (7 pa ) at −400mV. The voltammogram showed stability against repetitive scan cycles while the peak current showed increase with scan rates (100–200mV/s). The sensors show steady state peak enhancement (6.05–134.05pA) with DA concentration range of 0–100pM. The fabricated electrode is suitable for measuring DA with high sensitivity. The biodegradability of the prepared electrode is suitable for eco-friendly and disposable applications, which aligns with the green technology.

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