Abstract
Abstract Graphene and its derivatives have attracted much attention in recent years due to their unique properties and functionalization ability in tissue engineering. In this work, effect of biomolecule adding in three groups of Graphene family (consisting of Graphene, Graphene Oxide and reduced Graphene Oxide), their composites and modified forms are studied. Although the Graphene family induces differentiation of stem cells, adding appropriate factors (such as growth factors, inducers and gene activator proteins) helps improve the adhesion, proliferation and differentiation of cells. The novelty of this work is to verifying the capability of specifically-induced differentiation and bioactive controlled release of biomolecules on Graphene-based substrates, Graphene filled substrates or Graphene coated substrates and explaining the important role of biomolecules in stem cells fate. The study indicates that Graphene family can release biomolecules (including growth factors and proteins) in a controlled manner and these additives significantly enhance or accelerate the adhesion, proliferation and differentiation of stem cells and induce the differentiation of stem cells to specific cells.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
