Abstract
Backround: Twenty four 4-(4-substituted phenyl)-6-(furan-2-yl)-3,4-dihydro pyrimidin- 2(1H)-one,4-(4-substituted phenyl)-6-(furan-2-yl)-3,4-dihydro pyrimidin-2(1H)-thione and 4-substituted phenyl-3,4,5,6,7,8-hexa hydro quinazolin-2(1H)-one, 4-substituted phenyl-3,4,5,6,7,8-hexa hydro quinazoline-2(1H)-thione derivatives were constitute attractive targets for the development of active antimicrobial as well as antimycobacterial agent. Keywords: AntiTB, graph theoretical analysis, microbial pathogenic strains, pyrimidines, quinazolines.
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