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Abstract
The granulosa-theca cell tumor (GTCT) is the most common ovarian tumor of the horse. 4,7 Mares with a GTCT may exhibit continuous or intermittent estrus, stallion-like behavior or may remain anestrus. 4 The hormone secretory profile of the tumor dictates the behavior expressed, with mares having elevated plasma testosterone concentrations (>100 pg/ml) exhibiting stallion-like behavior. 7 The ultrasonic appearance of the affected ovary ranges from a homogenous echogenic mass to a multicystic or 'honeycomb' pattern. 1 The contralateral ovary is usually small and inactive, 4,7 although one mare with a functional contralateral ovary was recently described. 2 Mares with an inactive contralateral ovary resume normal cyclic ovarian activity 2-16 months after removal of the affected ovary 4 Clinical diagnosis of a GTCT is based on history, behavior, presence of a unilaterally enlarged ovary with an inactive contralateral ovary, and in some cases, elevated plasma testosterone concentrations. This report documents the presence of a granulosa cell tumor in two mares which exhibited normal follicular development, ovulation and luteal function in the contralateral ovary.
Published Version
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