Granuloma Annulare Associated With Cutaneous Marginal Zone Lymphoma

Abstract

Granuloma annulare and other granulomatous disorders have been reported to be associated with internal malignancies, primarily T-cell lymphomas, whereas very few reports of granulomatous disorders in association with B-cell lymphoma exist in the literature. We report a case of marginal zone lymphoma, a cutaneous B-cell lymphoma that occurred concomitantly with refractory granuloma annulare. This case highlights the importance of considering both B- and T-cell dyscrasias in the case of refractory or extensive granulomatous lesions and the importance of histopathologic examination in the evaluation of these lesions.