Abstract
BackgroundGranulocytic sarcoma (GS) is a form of acute myeloid leukemia (AML), also known as extramedullary myeloid tumor or chloroma. It forms a solid malignant tumor consisting of myelocytes or granulocytes and is typically located in bone while occurrence in other parts of the body is rare.Case presentationWe reported a 40-year-old male patient who had jaundice, highly elevated bilirubin, and a mass highly suspicious of pancreatic head carcinoma. We performed surgery and the pathology and immunohistochemistry suggested GS; however the blood test and the bone marrow infiltration showed no evidence of AML. In our review of the published reports of GS, we only found six reports of the GS in the pancreas, and we suggested that immunohistochemical staining should be used to accurately differentiate GS from other pancreatic cancer and other types of leukemia.ConclusionsThe accurate diagnosis of GS is necessary for determining prognosis and deciding appropriate therapy.
Highlights
Granulocytic sarcoma (GS) is a form of acute myeloid leukemia (AML), known as extramedullary myeloid tumor or chloroma
The accurate diagnosis of GS is necessary for determining prognosis and deciding appropriate therapy
Discussions and Conclusions Since 1966, about 1,000 cases of GS located outside bone had been published
Summary
Granulocytic sarcoma (GS) is a form of acute myeloid leukemia (AML), known as extramedullary myeloid tumor or chloroma. Background Granulocytic sarcoma (GS), called extramedulary myeloblastoma or chloroma, is a rare solid tumor composed of immature myeloid cells [1]. We hereby reported a case of GS in the pancreas, in a patient without AML. Case presentation The patient was a 40-year-old man.
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