Abstract
Both whole lung lavage (WLL) and inhaled granulocyte macrophage colony-stimulating factor (GM-CSF) have been shown to improve patient outcomes in pulmonary alveolar proteinosis (PAP). We report a case of autoimmune PAP that was refractory to bilateral WLL, relapsing rapidly after each of her 6 treatments. A systemic GM-CSF trial was also ineffective. Her seventh WLL was followed immediately by inhaled GM-CSF, and the patient experienced a complete and sustained remission. Our case suggests that those 2 treatments might have a synergistic effect.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Canadian Journal of Respiratory, Critical Care, and Sleep Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
