Abstract
Granular cell tumours (GCT) of the soft tissues are rare benign tumours but some time may be difficult to distinguish from malignant neoplasms. It is important that clinicians are aware of their existence. We present a new case of GCT of the soft tissues followed by a brief review of literature.
Highlights
Granular cell tumours are rare benign tumours and were first described by Weber in 1854 [1]
We describe a new case of soft tissue granular cell tumour in a 47-year-old woman, with a brief review of the literature
No evidence of malignancy was noted on the core biopsy
Summary
Granular cell tumours are rare benign tumours and were first described by Weber in 1854 [1]. Abrikossoff, in his publication of 1926 [2] reported the occurrence of granular cell tumour in the tongue. We describe a new case of soft tissue granular cell tumour in a 47-year-old woman, with a brief review of the literature. Ultrasound guided core biopsy of the lesion showed sheets of cells with abundant granular cytoplasm and small unremarkable bland nuclei. The patient underwent a wide surgical excision of the tumour and had an unremarkable post-operative recovery. The specimen submitted to pathology contained an irregular piece of soft tissue measuring 5 × 4.5 × 3 cm. Immunohistoichemistry showed S100 to be diffusely positive, while NSE faintly positive All these features were suggestive of granular cell tumour. Histology confirmed that excision margins were clear of the tumour. (Histopathology images are shown in figures 1 and 2)
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