Abstract

Aims: Granular cell tumor is an extremely rare tumor, accounting for 0.5% of all soft tissue tumors. This rare neoplasia have variable age, sex and ethnicity predilection. Positive staining for S-100 protein confirms the diagnosis and no harmonized treatment guideline is established. We report true this manuscript a rare case of benign of granular cell tumor of the hypopharynx. Materials and Methods: Case report. Results: We add to the literature arsenal of this entity by reporting this rare case of benign of granular cell tumor of the hypopharynx in A 74 years-old female patient with hypertension, suffered from dysphonia for about 6 months. Examination identified a budding tumor in the left piriform sinus. Ct scan showcased a 1 cm irregular, spontaneously hypodense, slightly enhanced after injection mass, infiltrating the left piriform sinus. Excisional biopsy confirmed the diagnosis and follow-up was uneventful. Conclusion: Originating from the Schwann cells; Granular cell tumor has nonspecific symptoms and usually displays as small, smooth, submucosal lesion. Variant of this tumor can be classified as either as synchronous or metachronous, or either malignant, begin or atypical.

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