GRANULAR CELL TUMOR OF THE DUODENUM

Abstract

Abrikossof first described granular-cell tumor (GCT) in 1926. This tumor most typically occurs in the skin, the tongue, and the breast. The GI tract is a less common site of occurrence. In the GI tract, the esophagus is the most frequent site, with nearly 200 cases reported. Considerably fewer GCTs have been reported in the large intestine, the stomach, and the biliary tract. Only two reports have noted the appearance of GCT in the duodenum. In 1981, Johnston and Helwig described a series of 74 GCTs from the GI tract and the perianal region. They listed one GCT from the duodenum, without a detailed description of clinical findings. Recently, Onoda et al reported a duodenal GCT presenting with significant GI bleeding and requiring surgical excision. We report a third case of duodenal GCT and discuss its management.