Abstract
Grand Challenges in Bioinformatics and Computational Biology
Highlights
The significance of this work, which was not yet called either bioinformatics or computational biology, was in the new discoveries of sequence similarities and patterns of gene evolution
With several more genome sequences of bacteria and, later, archaea, the approaches of bioinformatics and computational biology could be applied at the genomic scale
Our understanding of the organisms with completely sequenced genomes continues to be far from perfect, a significant amount of new information could be teased out of the very first genomes in a matter of few months – the concern that the genome sequences for a long time will remain an enigma, similar to Linear A script of Cretan archeologists, proved to be unfounded
Summary
The significance of this work, which was not yet called either bioinformatics or computational biology, was in the new discoveries of sequence similarities and patterns of gene evolution. With several more genome sequences of bacteria and, later, archaea, the approaches of bioinformatics and computational biology could be applied at the genomic scale.
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