Abstract
SPECIALTY GRAND CHALLENGE article Front. Genet., 19 January 2011 | https://doi.org/10.3389/fgene.2011.00001
Highlights
Most of the newly identified ncRNAs’ functions are unknown, but these transcripts are increasingly recognized as regulators of gene expression
The roles of ncRNAs are many and diverse. As they involve in the regulation of cellular differentiation and proliferation, the altered expression of key ncRNAs may lead to certain human diseases (Irminger-Finger et al, 2010)
Increasing number of studies indicate that miRNAs are emerging as important modulators in cellular pathways and they play a key role in human diseases (Cho, 2010a)
Summary
Most of the newly identified ncRNAs’ functions are unknown, but these transcripts are increasingly recognized as regulators of gene expression. MicroRNA (miRNA) is one important subcategory of ncRNAs. Most of these molecules appear to regulate target gene expression through translation repression or mRNA degradation (Cho, 2007). Increasing number of studies indicate that miRNAs are emerging as important modulators in cellular pathways and they play a key role in human diseases (Cho, 2010a).
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
