Abstract
The use of solutions for parenteral nutrition has greatly enhanced the management of medical and surgical disorders. Two general classes of solutions are employed: total parenteral nutrition solutions (TPN), containing a mixture of amino acids, glucose, electrolytes, and vitamins, and soybean oil emulsion (Intralipid). Both solutions have been shown to support the growth of bacteria and fungi. 1,2 Although sepsis is a recognized complication of the use of TPN solutions, 2 there have been no reports of infection with the use of lipid emulsion. We report two distinct episodes of lipid emulsion-associated sepsis with two different Gram-negative microorganisms in a chronically ill infant. Report of a Case .—An infant with complications resulting from a midgut volvulus required parenteral nutrition at 3½ months of age and a central venous catheter was inserted. Both glucose-amino acid (TPN) solution and lipid emulsion were administered via a Y configuration delivery system. A 0.22-μ particle
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