Grafted Semiflexible Nunchucks with a Magnetic Bead Attached to the Free End.

Abstract

Semiflexible nunchucks are block copolymers, which consist of two long blocks of high bending stiffness jointed together by a short block of low bending stiffness. Semiflexible nunchucks that consist of two DNA nanorods jointed by a short segment of double-stranded (ds) DNA and confined in two dimensions have been used in recent experiments by Fygenson and coworkers as a tool to magnify the bending fluctuations of the linking dsDNA, which in turn are used to deduce the persistence length of dsDNA. In a recent theoretical analysis, we showed that in a semiflexible nunchuck with one end grafted, the fluctuations of the position of the free end that is transverse to the grafting direction exhibit a pronounced bimodality, provided that the bending stiffness of the hinge is not very large. In this article, we theoretically analyse a grafted semiflexible nunchuck with a magnetic bead attached to its free end. We show that a transverse magnetic field induces an asymmetry in the bimodal distribution of the transverse fluctuations of the free end. This asymmetry is very sensitive to interactions with a magnetic field and, in principle, could be used in magnetometry (the measurement of a magnetic field or the magnetic moment of the bead). We also investigate how the response of the bimodal distribution of the transverse fluctuations of the free end to a magnetic field depends on the bending stiffness of the nunchuck hinge. In addition, we analyse the closely related systems of a single filament and two filaments jointed at a kink point with one end grafted and the other end attached to a magnetic bead.