Abstract

Introduction. The recombinant enzymes, produced through biotechnological processes, have different medical applications. Recently, though poorly documented, they have been applied in aesthetic medicine to improve certain conditions that significantly affect patients' appearance, image, and quality of life. Objective. To document the use of recombinant enzymes in cosmetic dermatology regarding indicators of patient satisfaction with the procedure. Material and Methods. In this article, a series of cases have been brought together to document the use of recombinant enzymes in managing flaccidity and fat accumulation in certain facial and body areas, including measuring satisfaction with the results. Results. Two hundred twenty-nine cases from a Latin American multicenter trial were documented from private clinical practice using a standardized data collection format and a guide for clinical photography. Discussion. Our findings in 229 Latin American cases show a high grade of satisfaction in the management of double chin, jowl, abdominal flaccidity, and flaccidity in the limbs, as well as a good aesthetic outcome with the use of the combination of collagenase, hyaluronic-lyas, and lipase. Conclusions. The use of recombinant enzymes in managing the indications studied in clinical practice in cosmetic dermatology and aesthetic medicine, based on their effects on tissues, both on the face and the body, is highly satisfactory, and their results are well evaluated.

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