Grade 1 and 2 Chondrosarcomas of the Chest Wall: CT Imaging Features and Review of the Literature.

Filippo Del Grande,Edward McCarthy,Shivani Ahlawat,Laura M. Fayad

doi:10.3390/diagnostics12020292

Filippo Del Grande, Edward McCarthy + Show 2 more

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https://doi.org/10.3390/diagnostics12020292

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Journal: Diagnostics	Publication Date: Jan 24, 2022
Citations: 2	License type: CC BY 4.0

Affiliation: Johns Hopkins University

Abstract

The purpose of our retrospective article is to review the CT imaging features of chondrosarcomas of the chest wall with pathologic correlation. For 26 subjects with biopsy-proven chondrosarcomas of the chest wall, two musculoskeletal radiologists retrospectively reviewed 26 CT scans in consensus. Descriptive statistics were performed. The mean tumor size was 57 mm. Twenty (20/26, 77%) chondrosarcomas were located in the ribs and six (6/26, 23%) in the sternum. The majority were lytic (19/26, 73%) with <25% calcification (15/26, 58%), and with a soft tissue mass (22/27, 85%). In this study CT features of grade 1 chondrosarcoma overlapped with those of grade 2 tumors. In conclusion, chondrosarcomas of the chest wall are generally lytic with an associated soft tissue mass, showing little calcified matrix and low-to-intermediate grade.

Highlights

Wall: CT Imaging Features and Chondrosarcomas (CS) of the chest wall are rare lesions, but they represent the most common primary malignant bone tumors of the chest wall [1,2]
Chondrosarcomas of the chest wall are generally lytic with an associated soft tissue mass, showing little calcified matrix and low-to-intermediate grade
There are, several reports in the surgical literature regarding the clinical features and prognosis of CS of the chest wall [5,8,13,18,19,20]. It is important for the imaging interpreter to consider CS in the differential diagnosis of a chest wall mass, especially due to the knowledge that some histologic features of CS can overlap with enchondroma, as has already been described in the extremities [21]

Summary

Introduction

Wall: CT Imaging Features and Chondrosarcomas (CS) of the chest wall are rare lesions, but they represent the most common primary malignant bone tumors of the chest wall [1,2]. There are, several reports in the surgical literature regarding the clinical features and prognosis of CS of the chest wall [5,8,13,18,19,20] It is important for the imaging interpreter to consider CS in the differential diagnosis of a chest wall mass, especially due to the knowledge that some histologic features of CS can overlap with enchondroma, as has already been described in the extremities [21]. The purpose of our study was to retrospectively review the CT imaging features of chondrosarcomas (CS) of the chest wall with pathologic correlation

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