Abstract
ObjectiveStudy of prevalence of gout with concomitant diseases. MethodsStudy population included all living persons in Stockholm County, Sweden, on January 1st 2013 (N=2,124,959). A diagnosis of gout was identified during 2013–2014, with information of diabetes mellitus and insulin resistance, hypertension, chronic heart failure, chronic kidney disease, alcohol abuse, and malignancies. Age-adjusted odds ratios (ORs) with 95% confidence intervals (95% CI) for women and men with gout, using individuals without gout as referents, were calculated. ResultsAge-adjusted odds of co-morbidities among individuals with gout vs. those without gout were: diabetes mellitus and insulin resistance 3.97 (95% CI 3.65–4.31) in women and 1.88 (95% CI 1.78–1.99) in men; hypertension 4.02 (95% CI 3.69–4.37) in women and 3.21 (95% CI 3.06–3.37) in men; chronic heart failure 4.72 (95% CI 4.31–5.19) in women and 2.84 (95% CI 2.66–3.04) in men; chronic kidney disease 2.08 (95% CI 1.50–2.87) in women and 2.39 (95% CI 2.15–2.66) in men; alcohol abuse 8.98 (95% CI 8.15–9.80) in women and 4.38 (95% CI 4.10–4.69) in men; and malignancies 1.32 (95% CI 1.17–1.48) in women and 1.13 (95% CI 1.06–1.21) men. ConclusionGout is a warning sign for concomitant diseases, e.g. alcoholism, diabetes, cardiovascular diseases, and cancer. Key messages1.A diagnosis of gout was present in 0.3% among women and 0.8% among men in Stockholm County.2.Among individuals with gout, hypertension, being the most common concomitant disease, was present in 68% among women and 54% among men.3.Alcohol abuse was the most overrepresented disorder compared to individuals without gout, with odds ratio of 9 among women and 5 among men.
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