Abstract
Gordon Life Science Institute is the first Internet Research Institute ever established in the world. It is a non-profit institute. Those scientists who really dedicate themselves to science and loving science more than anything else can become its member. In the friendly door-opened Institute, they can maximize their time and energy to engage in their scientific creativity. They have also believed that science would be more truthful and wonderful if scientists do not have to spend a lot of time on funding application, and that great scientific findings and creations in history were often made by those who were least supported or funded but driven by interesting imagination and curiosity. Recollected in this review article is its establishing and developing processes, as well as its philosophy and accomplishments. Particularly, its productive and by-productive outcomes have covered the following five very hot topics in bioinformatics and drug development: 1) PseAAC and PseKNC; 2) Disported key theory; 3) Wenxiang diagram; 4) Multi-label system prediction; 5) 5-steps rule. Their impacts on the proteomics and genomics as well as drug development are substantially and awesome.
Highlights
The Gordon Life Science Institute was established in 2003 and its cradle was in San Diego of California, USA
About a quarter of century later, the same name was used for the Institute, meaning that “Reform and Opening” and “Free Communication” can stimulate a lot of great creativities
Encouraged by the successes of using PseAAC to deal with protein/peptide sequences, the concept of PseKNC (Pseudo K-tuple Nucleotide Composition) [279] was developed for generating various feature vectors for DNA/RNA sequences that have proved very useful as well [268, 279-295]
Summary
The Gordon Life Science Institute was established in 2003 and its cradle was in San Diego of California, USA. Its mission is to develop and apply new mathematical tools and physical concepts for understanding biological phenomena. The Institute is a newly emerging academic organization in the Age of Information and Internet, founded by Professor Dr Kuo-Chen Chou, right after he was retired from Pfizer Global Research and Development in 2003. To make Swedish people easier to pronounce his name, Professor Chou used “Gordon” as his name in Sweden. About a quarter of century later, the same name was used for the Institute, meaning that “Reform and Opening” and “Free Communication” can stimulate a lot of great creativities
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