Abstract
Controlled ovarian stimulation (COS) with a LNG IUD in situ is safe without negatively impacting cycle outcomes.1 While the contraceptive mechanism of a LNG IUD is mainly due to local progesterone (P4) effect on the endometrium, P4 has known negative feedback to the hypothalamus and pituitary which can lead to anovulation and suppression of luteinizing hormone (LH).2 Increased utilization of GnRH-a triggers during COS requires adequate LH response. Are patients with LNG IUD at increased risk for poor response from GnRH-a triggers during COS?
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