Gold Therapy for Rheumatoid Arthritis

Abstract

Letters15 July 1991Gold Therapy for Rheumatoid ArthritisSeth H. Lourie, MDSeth H. Lourie, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-2-155 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors:Epstein and colleagues (1) raise some interesting and provocative points regarding gold therapy. Their presentation of the data, however, raises some serious questions of bias in interpretation. Specifically, one third of the patients are described as having received parenteral gold during the year before the study. This group is not further separated from the rest of the cohort when discussing patient characteristics at the beginning of the study. There is also a peculiar distribution of the number of patients who received gold during the first year of the study when compared with those who apparently began gold...Reference1. EpsteinHenkeYelinKatz WCEP. Effect of parenterally administered gold therapy on the course of adult rheumatoid arthritis. Ann Intern Med. 1991;114:437-44. LinkGoogle Scholar1. EpsteinHenkeYelinKatz WCEP. Effect of parenterally administered gold therapy on the course of adult rheumatoid arthritis. Ann Intern Med. 1991;114:437-44. LinkGoogle Scholar2. Lipsky P. Disease-modifying drugs. In: Utsinger PD, Zvaifler NJ, Ehrlich GE; eds. Rheumatoid Arthritis. Philadelphia: J.B. Lippincott Co.; 1985:601-35. Google Scholar3. Feinstein A. Clinical biostatistics. XXXV. The persistent clinical failures and fallacies of the UGDP study. Clin Pharmacol Ther. 1976;19:78-93. CrossrefMedlineGoogle Scholar1. Proceedings of the Biennial Regenstrief Conference. Methods for using large databases in health care research: problems and promises. Stat Med. 1991;10:505-670. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Prince George's Hospital Center Cheverly, MD 20785 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByTreatment of Rheumatoid Arthritis: Challenges to Traditional ParadigmsTheodore Pincus, MD, Frederick Wolfe, MD 15 July 1991Volume 115, Issue 2Page: 155-156KeywordsCohort studiesRheumatoid arthritis Issue Published: 15 July 1991 PDF DownloadLoading ...