Abstract
Gold preparations have recently found clinical application in tuberculosis and certain diseases of the skin. Among these preparations are Sanocrysin or gold and sodium thiosulfate, Krysolgan and Triphal.Sanocrysin or gold and sodium thiosulfate was originally prepared by Fordos and Gellis in 1845. It has been improved on by Mollgaard and contains about 37.5 per cent gold and 26.2 per cent sulphur, which would correspond to the formula 3Na2S2O3Au2S2O3 4H2O.Triphal, one of the other preparations studied by us from a toxicological point of view, contains approximately 44 per cent gold and 7.1 per cent sulphur, nd this corresponds to the chemical formula C6H3N-NH-CSAu-COONa 2H2O or the sodium salt of Aurothiobenzimidazolcarboxylic acid.Previous investigations1 have shown that under some conditions, gold salts tend to produce marked kidney and liver damage as well as urticaria, pruritus and erythematous eruptions. With these possibilities in mind, the present report deals with a toxicological study of the thre...
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