Gold Nanorods and Polymer Micelles Mediated Dual TLR Stimulators Delivery System CPG@Au NRs/M‐R848 Regulate Macrophages Reprogramming and DC Maturation for Enhanced Photothermal Immunotherapy of Melanoma (Small Methods 5/2023)

Abstract

Back Cover In article number 2201087, ZhiYong Qian and co-workers show that in the hybrid delivery systems [email protected] NRs/m-R848, immunogenic cell death (ICD) induced by Au NRs could synergistically produce an in-situ vaccination effect with CPG ODN and R848. By triggering dendritic cells maturation and macrophage reprogramming, this photothermal immunotherapy strategy holds great potential in generating systemic and lasting antitumor immunity by inhibiting tumor growth and metastases simultaneously.