Goat and Bovine Colostrum as a Basis for New Probiotic Functional Foods and Dietary Supplements

Hyrslova I,Krausova G

doi:10.4172/1948-5948.1000262

Abstract

Because bovine and goat colostrum are a rich source of essential nutrients for new-borns, their use in functional foods has substantially increased in recent years, but not in combination with probiotic bacteria. Therefore, our aim was to assess the possibility of combining goat or bovine colostrum with probiotics. First, we compared the immunomodulatory effect of both goat and bovine colostrum with that of human milk by the 3-day in vitro stimulation of human peripheral blood mononuclear cells (hPBMCs). Luminex multiplex analysis was used to analyze cytokine production by the hPBMCs. Although goat colostrum had a more similar immunomodulatory effect to human milk than bovine colostrum, we, nevertheless, decided to compare the potential of all three as growth substrates. Using the agar plate method, the growth of bifidobacteria, lactobacilli and enterococci was determined. Growth of Bifidobacterium sp. in goat colostrum is significantly better (P < 0.05) than in bovine colostrum or human milk. Our results indicate that goat colostrum has significant potential for the development of new functional foods and dietary supplements with bifidobacteria.

Highlights

Colostrum is defined as first milk with specific composition produced by mammals immediately after parturition
Oligosaccharides with prebiotic effect are naturally present in colostrum and can improve the growth of probiotic microorganisms such as lactobacilli and bifidobacteria [4]
Immunomodulatory effect of human milk, bovine and goat colostrum on human peripheral blood mononuclear cells were compared based on the production of pro-inflammatory and regulatory cytokine

Summary

Introduction

Colostrum is defined as first milk with specific composition produced by mammals immediately after parturition It contains high levels of bioactive components, including growth factors, immunoglobulins, lactoperoxidase, lactoferrin, lysozyme, immunomodulatory peptides, oligosaccharides and others [1,2]. The combination of health benefits of probiotics and colostrum can help to supply a market of food supplements and functional food with new products. For this reason, aims of the presented study were to test bovine and goat colostrum as growth substrate for selected probiotic microorganisms and compared the immunomodulatory effect of tested colostrum with human milk on human mononuclear cells

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