Abstract
Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ART which occurs more frequently in women with a high absolute or rapidly rising serum estradiol (E2) level or more than 25 follicles. Some have proposed withholding gonadotropins (coasting) as one strategy to reduce the likelihood of OHSS. We have reported the novel addition of GnRH antagonist to women suppressed with GnRH agonists as an alternate to coasting in a pilot study of 12 patients with ovarian hyperresponse. In these women treated with GnRH agonist, addition of GnRH antagonist resulted in a 35% reduction in E2 within 24 hours, allowed cycle continuation, and resulted in excellent pregnancy outcome without excess incidence of OHSS.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
