Abstract

Use of a gonadotropin-releasing hormone (GnRH) antagonist protocol with GnRH agonist (GnRHa) trigger for final oocyte maturation is the most effective strategy to reduce the rate of ovarian hyperstimulation syndrome (OHSS) during IVF. However, concerns persist regarding GnRHa trigger and ART outcomes. Use of a combination GnRHa and low-dose human chorionic gonadotropin (hCG) co-trigger has been reported to reduce OHSS and preserve IVF outcomes. The objective of this study was to examine the impact of final oocyte maturation method (GnRHa v co-trigger) on OHSS, oocyte yield and maturity.

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