GMP-Compliant Perinatal Tissue-Derived Stem Cells

Abstract

Regenerative medicine as a novel approach uses biological methods and products to regenerate, repair, replace, and enhance the lost function of an organ or tissue. Stem cells have a crucial role in regenerative medicine. Therefore, several sources of stem cells have been used for cell therapy, tissue engineering and regenerative medicine. Recently, perinatal stem cells as a promising cell source have been suggested for regenerative medicine. Their great advantages such as convenient accessibility, low immunogenicity, high proliferation capacity, and minimal ethical limitations have introduced them as a novel source for regenerative medicine. However, good manufacturing practice (GMP) is needed to provide these cells with defined quality, safety, and efficacy for clinical application. Like to other types of stem cells, perinatal stem cells manufacturing in accordance with GMP regulations and standards could provide a valuable source of stem cells for cell therapy and regenerative medicine.