Glycosylation Reactions in the Synthesis of Flavonoid Glycosides

Abstract

An overview of flavonoid glycoside synthesis has been provided with an emphasis on the construction of the glycosidic linkages. 1 Introduction 2 Synthetic Tactics 3 Synthesis of Flavonoid O-Glycosides 3.1 Glycosylation with Glycosyl Bromides 3.2 Glycosylation with Glycosyl Imidates 3.3 Glycosylation with Glycosyl Esters 3.4 Glycosylation with Glycosyl Fluorides 3.5 Combined Application of Different Types of Glycosyl Donors­ 4 Synthesis of Flavonoid C-Glycosides 5 Synthesis of Flavonoid Mixed O,C-Glycosides 6 Conclusion