Glycoprotein biosynthesis in animals infected with a myxovirus: II. Study of physicochemical parameters of liver N-acetylglucosaminyl transferase

Abstract

1. 1. When animals are infected by myxovirus, liver microsomic N-acetylglucosaminyl transferase activity is enhanced. 2. 2. Physicochemical parameters of this activity ( pH, temperature, sensibility to cations, detergents, nucleotidcs, nucleoside di- and triphosphates, antibiotics) are in favour of two differents enzymatic systems in normal and infected liver cells. 3. 3. In addition, the study of the localization of N-acetylglucosaminyl transferase shows that the enzyme of infected cells is more important in ‘ rough microsomes ’.