Abstract
Tear down the wall: Ready methods for the construction of libraries of both α- and β-aza-C-rhamnomimetics with high levels of diastereoselectivity have allowed the identification of inhibitors of rhamnosyl-processing enzymes. These include the first examples of analogues of the Mycobacterium tuberculosis sugar L-rhamnose that are inhibitors of mycobacterial biosynthetic pathways.
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