Abstract
Glycocalyx as Possible Limiting Factor in COVID-19.
Highlights
Specialty section: This article was submitted to Inflammation, a section of the journal Frontiers in Immunology
Knowledge on underlying molecular pathways is still scarce. In this opinion we would like to highlight the role of glycocalyx disturbance for endothelial cell infection possibly being the limiting factor to SARS-CoV-2 disease exacerbation
Besides the development of an acute respiratory distress syndrome (ARDS) in patients who are critically ill after infection with SARS-CoV-2, endothelial dysfunction seems to be an underlying cause of multiorgan failure
Summary
Specialty section: This article was submitted to Inflammation, a section of the journal Frontiers in Immunology. In this opinion we would like to highlight the role of glycocalyx disturbance for endothelial cell infection possibly being the limiting factor to SARS-CoV-2 disease exacerbation. Besides the development of an acute respiratory distress syndrome (ARDS) in patients who are critically ill after infection with SARS-CoV-2, endothelial dysfunction seems to be an underlying cause of multiorgan failure.
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