Glyco-helix: parallel lactose-lactose interactions stabilize an alpha-helical structure of multi-glycosylated peptide.

Abstract

Glyco-helix is designed as a novel model system to investigate cis carbohydrate-carbohydrate interactions. Adhesive Lac-Lac interactions stabilize alpha-helix of Lac-peptide in the presence of fluorinated alcohols, but no such an interaction was observed in GlcNAc-peptide.