Abstract
A green, metal-free and facile protocol has been developed by the three-component reaction of dimethyl acetylenedicarboxylate, aromatic amines and aldehydes with C-SO3H as an effective catalyst to afford diverse substituted dihydrofuran-3-carboxylates in high yields. The prominent features of this protocol are the catalyst reusability, wide range of functional group tolerance, shorter reaction time, no column chromatographic purification and easy work-up. The present one-step, cascade synthetic approach is straight forward that could avoid hazardous reagents and is turned to be a benign chemistry for the preparation of potent furan based molecules on a large scale.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
