Abstract
AimBetamethasone's effect on glucose homeostasis in the presence of gestational diabetes has not been adequately investigated. Materials-methodsWe assessed the glycemic profile of 99 women with gestational diabetes (52 on insulin, 47 on medical nutrition therapy) who were given betamethasone during hospitalization for at risk pregnancies. ResultsIn insulin-treated women the increase in total daily insulin dose significantly linked to betamethasone dose (p = 0.014). In women on diet, the need for insulin was positively related to betamethasone dose, age and gestational age >34th week (all p < 0.05). ConclusionParsimonious betamethasone use might still be beneficial with a milder effect on glycemia.
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