Glycemic changes after sleeve gastrectomy in type 2 diabetic morbidly obese patients

Abstract

Aims: Obesity is gradually turning into an epidemic condition throughout the world and has become a social psychological and economic burden of growing proportions. Bariatric surgery is known to be a highly effective and long lasting treatment for morbid obesity and many related conditions, including type 2 diabetes mellitus (T2DM) and the metabolic syndrome (MS). The aim of this study is to assess the short- and longterm effects of laparoscopic sleeve gastrectomy (LSG) on body weight and glucose homeostasis in morbidly obese diabetic patients. Methods: That study was conducted on 40 patients, for the evaluation of the short- and long-term effects (one-day, three-month, six-month, nine-month and twelve-month) of LSG on body weight and glucose homeostasis by measuring fasting blood glucose level, postprandial blood glucose (PPBG), glycated hemoglobin (HbA1C), insulin level in morbid obese T2DM subjects not adequately controlled with medical therapy. Results: Resolution incidence by all parameters (FBG, PPBG and HbA1C) was 13 patient (32.5%), 27 patients (67.5%), 32 patients (80%) and 32 patients (80%) at third-month, sixth-month, ninth-month and 12th-month postoperatively, respectively. Conclusion: In our study, the surgical procedure of laparoscopic sleeve gastrectomy resulted in marked weight loss and