Glycaemic and insulinaemic responses of adult healthy warm-blooded mares following feeding with Jerusalem artichoke meal.

Abstract

This study aimed to investigate the impact of the supplementation of a pre-biotic compound [Jerusalem artichoke meal (JAM)] on the glycaemic and insulinaemic response in healthy, non-obese warm-blooded horses. Six adult mares [mean body weight (bwt) 529±38.7kg; body condition score 5.1±0.49/9] were used. In two equal meals per day, the horses received crushed oat grains (1g starch/kg bwt per day) and meadow hay (2kg/100kg bwt per day) which together were likely to meet the energy recommendation for light work (GfE, ). Additionally, they received either 0.15g fructo-oligosaccharides and inulin (FOS+INU)/kg bwt per day via commercial JAM or maize cob meal without grains as control (CON) in 2×3-week periods according to a crossover design. Blood was collected on d21 of the feeding period at different ante- and postprandial (PP) time points (-60, 0, 30, 60, 90, 120, 180, 240 and 300min), and the plasma glucose and serum insulin levels were determined. Feeding JAM vs. CON did not change the PP peak of glucose or insulin (glucose: 6.3±0.40 vs. 7.0±0.87mmol/l; insulin: 0.508±0.087 vs. 0.476±0.082nmol/l) nor did it cause different AUCs until 120 and 300min PP for glucose and insulin, respectively (AUC120 , glucose: 997±41.6 vs. 1015±41.63mmol/l per minute, insulin: 49±6.3 vs. 42±6.3nmol/l per minute; AUC300 , glucose: 1943±142.3 vs. 2115±142.3mmol/l per minute, insulin: 94±14.8 vs. 106±14.8nmol/l per minute; p>0.05). Following JAM vs. CON feeding, glucose and insulin levels declined more rapidly until 240min PP and tended to be lower (p=0.053 and p=0.056, respectively) at this time point. This result might be promising and should further be studied more detailed.