Abstract
s / Digestive and Liver Disease 46 (2014) e85–e127 e109 GLUTEN FREE DIET OR NOVEL THERAPY: WHAT PARENTS OF CELIAC CHILDREN WANT Lorenzo Norsa1,∗, Carolina Tomba1, Carlo Agostoni2, Federica Branchi1, Maria Teresa Bardella1, Dario Conte1, Luca Elli 1 1 Centro per la Prevenzione e Diagnosi della Malattia Celiaca UOC Gastroenterologia ed Endoscopia, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Universita degli Studi di Milano, Milano, Italy 2 Clinica Pediatrica II, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Universita degli Studi di Milano, Milano, Italy Objective: Treatment for celiac disease (CD) is a strict, life-long gluten-free diet (GFD), which leads to rapid clinical improvement. Nevertheless, novel therapeutic approaches are under development. Our study evaluate the GFD impact as perceived by parents of CD children and their demand for alternative therapies. Methods: Parents of CD children were asked to fill a questionnaire investigating compliance and personal judgment on GFD, health status (HS) and quality of life (QOL), necessity and preference for novel therapies, eventual enrollment of their children in clinical trials. Results: 116 questionnairewere collected. GFD compliancewas 97.4% and was considered positively by 93.8% of the parents. HS and QOL significantly improved on GFD (p 10 ULN, EMA) could be diagnosed with CD omitting the duodenal biopsy. Considering that the average cost of performing an upper gastrointestinal endoscopy with duodenal biopsy is 284 Euro per patient, the new ESPGHAN protocol could have reduced our health care costs by 34.932 Euro over a 3 year period. Conclusions: We estimate that applying the new ESPGHAN criteria, almost50%of thechildrendiagnosedwithCD inourdepartment every year could receive the diagnosis without performing a duodenal biopsy and therefore eliminating possible risk related to this invasive procedure and drastically reducing health care costs. http://dx.doi.org/10.1016/j.dld.2014.07.117
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
