Abstract

Gluten-free diet (GFD) is the cornerstone treatment for celiac disease (CD). GFD implies a strict and lifelong elimination from the diet of gluten, the storage protein found in wheat, barley, rye and hybrids of these grains, such as kamut and triticale. The absence of gluten in natural and processed foods, despite being the key aspect of GFD, may lead to nutritional consequences, such as deficits and imbalances. The nutritional adequacy of GFD is particularly important in children, this the age being of maximal energy and nutrient requirements for growth, development and activity. In recent years, attention has focused on the nutritional quality of gluten-free products (GFPs) available in the market. It is well recognized that GFPs are considered of lower quality and poorer nutritional value compared to the gluten-containing counterparts. The present review focuses on the nutritional adequacy of GFD at the pediatric age, with the aim being to increase awareness of the potential complications associated with this diet, to identify strategies in order to avoid them and to promote a healthier diet and lifestyle in children with CD.

Highlights

  • Celiac disease (CD) is a chronic systemic autoimmune disorder caused by a permanent intolerance to gluten proteins in genetically susceptible individuals

  • With regards to lipid content and composition, Caponio et al showed that commercially available GF biscuits are richer in saturated fatty acids compared to the gluten containing equivalents [13]. All these characteristics have a negative effect on health, and this should be seriously taken into account, because the limited choice of food products in the diet of children with celiac disease (CD) induces a high consumption of packaged gluten-free products (GFPs), such as snacks and biscuits

  • The results showed that CD subjects followed a high-protein and high-lipid diet with low intakes of carbohydrates, iron, calcium and fiber compared to the recommended daily intakes

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Summary

Introduction

Celiac disease (CD) is a chronic systemic autoimmune disorder caused by a permanent intolerance to gluten proteins in genetically susceptible individuals. Gluten is a general term used to describe a mixture of storage proteins, including prolamins, hordeins and secalins found in wheat, barley and rye, respectively. These proteins may exert a toxic effect on intestinal mucosa in genetically susceptible individuals by triggering an immune-mediated response, responsible for the typical villous atrophy and lymphocyte infiltrate in small intestine mucosa seen in CD. The commercially available gluten-free (GF) products are processed foods purified of gluten The elimination of this storage protein inevitably alters the macro- and micro-nutrient composition, the nutritional value. Numerous foods available in supermarkets and grocery stores, including meat products, sweets and beer, contain gluten

Macronutrients
Micronutrients and Minerals
Dietary Fiber
Nutritional Imbalances in Children with Celiac Disease Following a GFD
Effects of Gluten-Free Diet on Anthropometric Parameters
Education and Compliance
Dietary Intake
Gluten-Free Foods
Pseudo-Cereals and Minor-Cereals
Vitamins and Minerals
Nutritional Follow-Up
Conclusions
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