Abstract

OPINION article Front. Pharmacol., 05 August 2014Sec. Experimental Pharmacology and Drug Discovery Volume 5 - 2014 | https://doi.org/10.3389/fphar.2014.00180

Highlights

  • Parasitic organisms establish a symbiotic association with individuals of a different species—the host—to obtain the metabolic resources needed for their survival and reproduction

  • We focus on a comparative analysis of a peculiar strategy of host physiological regulation, targeting the redox homeostasis, which appears to modulate parasitic interactions both at the organism and cellular level

  • Insect studies, dealing with parasitism of aphids, have shown that the disruption of host GSH pool and metabolisms significantly contributes to its physiological regulation and castration (Pennacchio and Mancini, 2012)

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Summary

Introduction

Parasitic organisms establish a symbiotic association with individuals of a different species—the host—to obtain the metabolic resources needed for their survival and reproduction. We focus on a comparative analysis of a peculiar strategy of host physiological regulation, targeting the redox homeostasis, which appears to modulate parasitic interactions both at the organism and cellular level.

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Conclusion
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