Abstract
Objective. To use an immunohistochemical method to study glutamine synthetase (GS)-synthesizing brain cells. Materials and methods. Enzyme was detected on frontal rat brain sections (n = 10) using mouse monoclonal antibodies. Specimens were analyzed by light and confocal laser microscopy. Results. GS was found to be expressed in all areas of the brain, mainly by two types of cells, with different structures and topographies. The main type of cell with immunopositive reactions to glial fibrillary acidic protein were identical to astrocytes. The other structural and locational type of cell differed from typical astrocytes. Conclusions. The data obtained here provide evidence that GS is not a selective marker for any particular population of rat brain cells.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.