Abstract
Rationale: Protein energy malnutrition in sepsis leads to increased mortality and complication rate. The vicious cycle between sepsis and malnutrition is linked to unfavorable outcome. Glutamine deficiency was found in malnourished and high inflammation condition such as emergency surgery. Glutamine, an amino acid, becomes essential in hypercatabolic condition and acts as a fuel for immune system; however, its benefit in sepsis is still debatable.
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